Principal Scientist

Principal Scientist

Biotechnology Clinical Life Sciences

Location Australia

Salary £50,000 - £65,000

Contract Permanent

Reference HMPSAu

Date Posted


Apply now

3 weeks left to apply

We have an exciting new opportunity for a highly experienced Principal Scientist at a leading CRO based in Australia. The ideal candidate will have proven experience in LCMS/MS assay development with working knowledge in a regulated, GLP bioanalytical laboratory.

Key Responsibilities and Duties:

  • Perform Principal Research and Development Scientist duties in the LCMS bioanalytical lab; 50–60 % lab duties, remainder office duties
  • Develop analytical methods using mass spec (LCMS/MS) as a detection tool to accurately measure and analyse the percentage of a drug in samples (NCEs)
  • Research and develop methods for profiling and analysing endogenous compounds in biological extracts using tandem mass spectrometry; document all methods
  • Develop and validate analytical methods to support drug analysis
  • Design LCMS/MS protocols for drug optimisation, method development and the processing of analytical runs
  • Manage high-level project tasks including project & client management to ensure agreed project timelines are met
  • Manage sample processing including receipt and disposal of study
  • Manage all scientific content of assigned studies
  • Provide technical expertise on troubleshooting across the regulated bioanalysis laboratory (method validation and study sample analysis)
  • Prepare and review bioanalytical reports
  • Liaise with clients including on-site visits, as well as perform audits when required
  • Provide leadership and supervision, as well as training of Analytical Scientists as required
  • Contribute to the Continuous Improvement in compliance, productivity and efficiency of the laboratory team
  • Participate in weekly resourcing meetings with senior staff to optimize resourcing across the laboratory

Ideal Skills and Qualifications:

  • Degree qualified, or equivalent, in a relevant scientific discipline
  • 5 – 10 years’ experience in LCMS/MS development, performing regulated bioanalysis and Assay Development (Tandem Mass Spec, LCMS/MS, IA)
  • Proven experience in a GLP environment within a CRO
  • Demonstrated ability to mentor, train and supervise
  • Experience in Watson LIMs in bioanalytical report writing would be an advantage
  • Ability to work effectively both in isolation and as part of a team
  • Ability to analyse problems, formulate effective solutions and coordinate tasks simultaneously

The company is a Contract Research Organisation specialising in providing drug development services for the pharmaceutical and biotechnology industries. You will be working in their state-of-the-art facilities based in Adelaide, Australia, with Visa and relocation support provided.

If you are interested or have any questions about this role, feel free to contact Harriet at CY Partners.

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Principal Scientist

Biotechnology Clinical Life Sciences

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3 weeks left to apply

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